BioProcessing Fittings PharmaLok Clamps

PharmaLok™ Clamps

State-of-the-Art Design Allowing for Easy Operation

The biopharmaceutical industry has made a strong move towards single-use technology, so Nordson MEDICAL has developed ground-breaking clamp designs that simplify the assembly process by making it effortless to securely attach sanitary fittings to bag ports and filters.

PharmaLok™ clamps are ASME BPE compliant and operate at a maximum pressure of 80 psi. Single-use and easy-open clamp sizes fit .5" (12.7 mm) to .75" (19.0 mm), 1" (25.4 mm) to 1.5" (31.8 mm), 3" (76.2 mm), and 4" (101.6 mm). These clamps provide a significant advancement for the industry, as a number of existing solutions either require tools for closure or consist of multiple components, which turns what should be a simple operation into a difficult and awkward process.

"As a founding member of BPSA, Nordson MEDICAL has been fortunate enough to have insight into the needs of the biopharm industry," comments Ken Davis, Global Marketing Manager for Nordson MEDICAL. "User-friendly solutions are increasingly demanded, and single-use systems have developed into an overwhelming market trend. Incorporating these factors into the PharmaLok™ has resulted in an ideal solution for our customers."

Easily operated with one hand, PharmaLok's patented design allows effortless attachment of fittings to bag ports and filters. The user simply rests the fitting in the PharmaLok's regulation-sized slot, lightly grips the surrounding handles, and listens for the sound of clicks to confirm a secure connection.

Meet Our New Clamps

To simplify assembly processes, Nordson MEDICAL has developed new 3" and 4" PharmaLok™ clamps. These ground-breaking clamp designs make it easy to securely attach sanitary fittings to bag ports and filters. The 4" clamp features a unique double-hinge that has been designed to provide equal pressure on the gasket as well as reduce the risk of accidental opening. As part of Nordson MEDICAL's PharmaLok™ line of clamps, these new products have all the features users have come to rely on, such as one-handed closure, audible clicks to indicate a secure connection, ASME-BPE compliance, and materials that meet USP Class VI and ISO 10993 criteria.

Do more with your pharmaceutical development, and utilize Nordson MEDICAL's industry-leading line of PharmaLok™ clamps. Complete the assembly by adding one of our sanitary fittings and end caps.

Request Samples

Design Upgrades for Improved Performance

As the global expert in the design, development and manufacturing of complex medical devices and component technologies, Nordson MEDICAL is committed to the continuous improvement of our products. This commitment to quality has improved the performance of our PharmaLok™ line of easy-open clamps and tube clamps.

These design upgrades include rounded hinges on all easy-open and tube clamps — allowing users to open these clamps to a full 180°, making it easier to insert both conforming and non-conforming fittings. To prevent the clamps from coming apart when completely opened, the hinges have also been enlarged.

As a result, the entire product line of PharmaLok™ easy-open clamps and tube clamps make end-user interaction easier and more consistent.

PharmaLok Design Changes

Features & Benefits

  • Effortlessly, securely attaches sanitary fittings to bag ports and filters
  • Easy, one-handed closure—no tools needed
  • Materials meet USP Class VI & ISO 10993 criteria
  • ASME BPE 018 DT-7-1 compliant & DIN compliant
  • Repeatable use with consistent pressure on the gasket
  • Tamper evident and zip-tie compatible
  • Use with gamma, autoclave, & x-ray sterilization
  • Audible clicks when securely connected
  • 360° compression
  • Connects both plastic & stainless steel fittings
  • SIP/CIP compatible
Visit Online Store

PharmaLok™ Clamps Technical Information

  • Glass-filled nylon
  • Autoclavable up to 273° F (134° C) for a maximum of 30 min
  • Gamma radiation up to 50 kGy
  • X-ray sterilization compatible up to 50 kGy
Sizes Fitting
  • .5" (12.7 mm) to .75" (19.0 mm)
  • 1" (25.4 mm) to 1.5" (38.1 mm)
  • 3" (76.2 mm)
  • 4" (101.6 mm)
Maximum Pressure
  • 80 psi (5.5 bar)
    • Conforms to ASME BPE-2022
  • Normal operating temperature -94° F (-70° C) to 140° F (60° C)
  • Cryogenic freezing to -112° F (-80° C)
See Related Resources
Shop All PharmaLok™ Clamps
Online Store